Avrdude: ser_open(): can't open device "\\.\COM5": acces denied

OK, based on the pin count it's a CH340.

Which driver version does Windows device manager report. If it had 2024 in the version, you can try to roll back the driver. Instructions e.g. here: Port monitor error: command 'open' failed: Invalid serial port. Could not connect to COM serial port - #49 by ptillisch.

Note
Those unmarked ICs are possibly rejected dies and a 3rd party buys them and packages them.