Node MCU Esp8266 12E Module error messages

When I am uploading any code onto my NodeMCU 1.0 (ES0-12E Module), I am getting this error message:
Connecting......................................_____
A fatal esptool.py error occurred: Failed to connect to ESP8266: Timed out waiting for packet header
Please help me resolve this issue

Have you tried restarting the IDE, make sure no other copies of the IDE are running. I see this error occasionally and retrying or restarting a few times makes it eventually work.

Does any wires/modules still connected to your ESP8266 during upload?

The ESP8266 modules sometimes still require you to reset the board while holding down the 'boot' button before trying to upload.