Differential Air Pressure sensing (Guidance needed)

I think you're trying to get blood from a stone. The MPXV7002DP states a 2.5% accuracy in its output, or about 6 bits of accuracy.

@others thanks for the suggestions.
@chagrin,can you explain?

Page 2 of the datasheet states that the output (voltage) signal accuracy is +/- 2.5% over the full scale span. So if you're powering it with 5V, have it connected to two vessels with equal pressure, you would want to see 2.5V. However, the accuracy of the device means it could output 2.5V plus or minus (2.5% * 5VFSS =) .125V.

The Arduino's 10bit ADC is already capable of measuring increments of (5V / 1024 bits =) .005V so it's already capable of measuring the pressure sensor's output much more precisely than the pressure sensor is accurate.

I think you're trying to get blood from a stone. The MPXV7002DP states a 2.5% accuracy in its output, or about 6 bits of accuracy.

That depends on whether hemilshah is looking for 13-bit accuracy, or 13-bit resolution. He wrote earlier:

if I have a pressure difference of say 0.1 or 0.001 kPa,will it be able to detect it?
Because I'll be using this to detect small pressure variations.

To me that suggests he needs to know if his pressure has changed by an amount in the order of 1Pa, not that he can measure to an accuracy of 1Pa. I don't know what he's measuring pressure for, but his process may be more sensitive to variation than to the actual mean value of pressure difference.

But of course, if he needs better than 2.5% accuracy, then he'll either need to calibrate or pick another sensor.