SN74141N driver doesn't work correctly with nixie tubes

Check the high voltage power supply. If the voltage is too high then the clamp diodes of the driver chips cut in and you get multiple cathodes lighting on the tubes. I guess that about 170 volts is correct for those tubes.

That is a nice looking clock by the way. I have 3 working nixie clocks and the components for two more. One I published here: Six Digit Nixie Clock