avrdude: Version 6.3-20190619
Copyright (c) 2000-2005 Brian Dean, http://www.bdmicro.com/
Copyright (c) 2007-2014 Joerg Wunsch
System wide configuration file is "C:\Users\joshu\AppData\Local\Arduino15\packages\arduino\tools\avrdude\6.3.0-arduino17/etc/avrdude.conf"
Using Port : COM5
Using Programmer : arduino
Overriding Baud Rate : 115200
avrdude: ser_open(): can't open device "\.\COM5": The semaphore timeout period has expired.
That is probably a windoz driver problem or a cable problem. Can you check the UNO and cable on another machine? If so that will narrow down the problem. Try a different cable, some are for charging only and will not work. I am assuming there is nothing currently connected to the UNO other then the USB cable.