Conflict Between RGBmatrix.h and and Wire.h

I am trying to use Wire.h to send communication from a Mega to an UNO. I am able to get the two boards communicating successfully. However, when I add the RGBmatrix.h library and try to print something to the matrix. None of the LEDs turn on.

As soon as the wire.h matrix is removed, I am able to print to the matrix.

Does anyone know what this conflict could be?

Details matter.