Can't see a problem with the reset line as you have included the 10k pull-up. Keep in mind that connecting and disconnecting the serial interface if the port is open at the time, will cause a reset.
You certainly did get the crystal close to the chip - as it is supposed to be. While the crystal should have a ground surrounding its connections, you want to space that ground away from the connections to minimise load capacitance.
I presume you are expecting to socket the main chip and thus have the crystal and other components inside the socket profile. If you are going into production and decide not to use sockets (as there should be no reason to replace the chip; it can be programmed in-circuit and sockets are a source of failure) then that would be a problem.
And as others have pointed out, you should have ground fill on both sides, and enough ground vias linking "fill" lands of any size to form a redundant net.