Upload to Pro Mini fails: "avrdude: stk500_recv(): programmer is not responding"

A friend has been using the Arduino Pro Mini in several products he builds. I volunteered to help him and got involved with the Arduino world a couple of years ago. I have not looked at the Pro Mini for about 18 months., but yesterday I wanted to try an experiment with the Pro Mini and found it (they) would no longer program. This morning I tried all the different Arduino varieties I own and found the Mini Pro is the only one that will no longer program:

              Board                             Device Manager reports            Programmer in IDE    
ESP32 WROOM-DA                        COM11 CH340                              ESPtool                 
Arduino Nano ESP32                    USB Serial Device COM9             ESPtool                 
Arduino Nano Every                      COM13 Arduino NANO Every    Onboard Atmel mEDBG     
Arduino Nano Every (#2)              COM7 Arduino NANO Every       Onboard Atmel mEDBG     
Arduino UNO R4 Minima              USB serial port (COM4)               (4 selections)          
Elegoo UNO R3                               Arduino UNO (COM5)                 (15 selections)         
                                                                    
All succeeded loading and executing the "Blink" program                                 
                                                                    
Arduino Pro Mini (5 examples)     USB serial port (COM12) (FTDI)    (15 selections)         
Pro Mini Clone                                 USB serial port (COM12)               (15 selections)         
                                                                    
Pro Minis all failed upload with “avrdude: stk500_recv(): programmer is not responding……”                                  

(Sorry about the formatting)
I successfully programmed all of these Mini Pros last year many times. I just checked and the FTDI drivers are the current version. I am using IDE 2.3.4 on a Windows 10 computer.

My friend will check to see whether he can still program the Mini Pro and I will pass along the data.

Any helpful comments are appreciated.

Hi @thedispatcher. Please provide a detailed description of how you are interfacing the Pro Mini with the computer.

For example, you might be using one of these modules:

Or maybe one of these cables:

📷

FTDI Cable.jpg by oomlout - CC BY-SA 2.0

In addition to the description of the USB to serial "bridge" hardware, we need to know how it is connected to the Pro Mini.

to prevent this you can do this :

  1. try burning bootloader of your arduino and check if the led blinks.
  2. try using the correct port and download ch340 driver
    3.try plugging and unplugging your arduino from your pc.

Please study Arduino a little bit and don't copy ideas from ChatGPT.